A composition for the treatment of heart failure comprising...

Details A composition for the treatment of heart failure comprising... A composition for the treatment of heart failure comprising...

A - Human Necessities

61

K

A61K 31/501 (2006.01) A61K 33/06 (2006.01) A61K 33/42 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2437196

A combination therapy for the treatment of heart failure, particularly acute heart failure, comprises administering a combination of levosimendan or a pharmaceutically acceptable salt thereof and a calcium ion source and/or an intracellular calcium increasing agent to a patient. The combination shows a synergistic effect even at doses having no effect if administered alone.

L'invention porte sur une thérapie combinée de traitement de l'insuffisance cardiaque, en particulier aiguë consistant à administrer au patient une combinaison de lévosimendan ou de ses sels pharmacocompatibles, et une source d'ions calcium et/ou un agent d'accroissement du calcium intracellulaire. Cette association à un effet synergique même à des doses n'agissant pas seules.

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