A composition for treating neurocerebrovascular disorders

A - Human Necessities – 61 – K

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A61K 36/9066 (2006.01) A61K 31/12 (2006.01) A61K 31/121 (2006.01) A61P 9/10 (2006.01) C07C 49/203 (2006.01) C07C 49/647 (2006.01)

Patent

CA 2473874

The present invention relates to A composition obtained from the lipid soluble extract of rhizomes and leaves of Curcuma species of Zingiberaceae family, useful for the treatment of neurocerebrovascular disorders, said composition comprising fraction A consisting of arturmerone of formula (1), and turmerone of formula (2), and/or along with fraction B consisting of curcumene and zingiberine, and/or fraction C consisting of germacrone, curcumerone, zedoarone, sedoarondiol, isozdedoaronidiol, curcumenone, and curlone, and/or pharmaceutically acceptable additives and a method of treating neurocerebrovascular disorders in animals including humans using said composition by administering therapeutically effective amount of lipid soluble extract.

La présente invention concerne une composition obtenue à partir de l'extrait liposoluble de rhizomes et de feuilles d'une espèce Curcuma de la famille des Zingibéracées, cette composition étant utile pour traiter des troubles neurocérébrovasculaires. Ladite composition comprend une fraction A, constituée d'ar-turmerone de formule (1) et de turmerone de formule (2), et/ou une fraction B, constituée de curcumene et de zingiberine, et/ou une fraction C, constituée de germacrone, curcumerone, zedoarone, sedoarondiol, isozdedoaronidiol, curcumenone et curlone, et/ou des additifs pharmaceutiquement acceptables. L'invention concerne en outre une méthode pour traiter des troubles neurocérébrovasculaires chez les animaux, y compris chez l'homme, au moyen de cette composition, cette méthode consistant à administrer une dose thérapeutique efficace d'extrait liposoluble.

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