A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01)
Patent
CA 2658474
The current invention is related to a conjugate comprising one or more antifusogenic peptides and an antibody against an HIV gp120 binding cell surface receptor, characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of said antibody against an HIV gp120 binding cell surface receptor and to the pharmaceutical use of said conjugate.
La présente invention concerne un conjugué contenant un ou plusieurs peptides antifusiogènes et un anticorps dirigé contre un récepteur de surface cellulaire se liant à la glycoprotéine gp120 du VIH, caractérisé en ce qu'un à huit peptides antifusiogènes sont chacun conjugués à une extrémité terminale des chaînes lourdes et/ou des chaînes légères dudit anticorps dirigé contre un récepteur de surface cellulaire se liant à la gp120 du VIH. L'invention concerne également l'utilisation pharmaceutique dudit conjugué.
Brandt Michael
Fischer Stephan
Kopetzki Erhard
Sankuratri Suryanarayana
Schumacher Ralf
Borden Ladner Gervais Llp
F.hoffmann-La Roche Ag
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