A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/52 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 38/17 (2006.01) A61K 38/27 (2006.01)
Patent
CA 2424896
A parenterally administrable, biodegradable microparticle preparation, preferably composed of amylopectin-containing starch. The preparation contains a biologically active substance which, during the first 24 hours after injection, exhibits a release of the active substance that is less than 25 % of the total release, determined from a concentration-time curve in the form of the ratio between the area under the curve during the said first 24 hours and the total area under the curve in question.
L'invention concerne une préparation de microparticules biodégradables pouvant être administrées par voie parentérale composées de préférence d'amidon contenant de l'amylopectine. La préparation contient une substance bioactive qui, pendant les 24 heures suivant l'injection, présente une libération de la substance active inférieure à 25 % de la libération totale, déterminée à partir d'une courbe de concentration-temps se présentant sous la forme du rapport entre la zone située au-dessus de la courbe pendant les premières 24 hures et la zone totale située sous la courbe en question.
Bjorn Soren
Drustrup Jorn
Gustafsson Nils Ove
Jonsson Monica
Laakso Timo
Jagotec Ag
Pacira Pharmaceuticals Inc.
Sim & Mcburney
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