A controlled, sustained release delivery system for smoking...

Details A controlled, sustained release delivery system for smoking... A controlled, sustained release delivery system for smoking...

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 9/16 (2006.01) A61K 9/70 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2102507

2102507 9219241 PCTABS00017 A drug delivery system useful in aiding individuals in the cessation of smoking or chewing nicotine containing products is described. The delivery system includes a physical constraint modulation system (PCMSTM) containing lobeline. The drug delivery system is capable of delivering lobeline to an individual in a controlled, sustained release manner and providing long-term therapeutic levels of lobeline to the individual. The delivery of lobeline in such a manner reduces or eliminates the individual's smoking or chewing habit. The PCMS may be a biodegradable polymer containing the lobeline capable of subcutaneous or intramuscular injection or implantation into the individual or may be part of a transdermal patch containing lobeline. Also described are methods of using the drug delivery systems and kits containing the drug delivery systems.

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