C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01)
Patent
CA 2741927
The present invention relates to a novel crystalline form of lenalidomide having formula (I) and chemically known as 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione. The present invention further relates to a process for the preparation of said novel form and its use in pharmaceutical preparations for the treatment of autoimmune disease, inflammation, inflammatory disease and diseases such as cancer, in particular the management of multiple myeloma.
La présente invention porte sur une nouvelle forme cristalline du lénalidomide répondant à la formule (I), connu sous la dénomination chimique 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-pipéridine-2,6-dione. La présente invention porte en outre sur un procédé de préparation de ladite nouvelle forme et sur son utilisation pour des préparations pharmaceutiques destinées au traitement d'une maladie auto-immune, d'une inflammation, d'une maladie inflammatoire et de maladies telles que le cancer, en particulier pour la prise en charge du myélome multiple.
Bhosale Priyanka
Gore Vinayak
Pehere Ashok
Shukla Vinay
Generics [uk] Limited
Osler Hoskin & Harcourt Llp
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