A crystalline form of the zoledronic acid, a process to...

Details A crystalline form of the zoledronic acid, a process to... A crystalline form of the zoledronic acid, a process to...

C - Chemistry, Metallurgy

07

F

C07F 9/6506 (2006.01) A61K 31/675 (2006.01) C07F 9/38 (2006.01)

Patent

CA 2615418

This invention refers to a new crystalline form of the Zoledronic acid, characterized by its X-rays diffractogram as well as by its spatial atomic distribution in the red crystalline and its curves of thermal analysis. There is also included a method to obtain this crystalline form, which includes the synthesis of the corresponding acid and the pharmaceutical composition this crystalline form comprises.

L'invention concerne une nouvelle forme cristalline de l'acide zoledronique, qui se caractérise par son diffractogramme aux rayons X ainsi que par sa distribution atomique dans l'espace dans le rouge cristallin et ses courbes de l'analyse thermique. L'invention concerne également un procédé permettant d'obtenir cette forme cristalline, qui consiste notamment en la synthèse de l'acide correspondant et de la composition pharmaceutique que cette forme cristalline renferme.

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