A cyclic hepta-peptide derivative from colonial ascidians,...

C - Chemistry – Metallurgy – 07 – K

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C07K 7/06 (2006.01) A61K 38/08 (2006.01) A61K 38/12 (2006.01) C07K 7/56 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2252099

A new cyclic heptapeptide, trunkamide A, with antitumor activity has been isolated from a Lissoclinum sp. collected on the Great Barrier Reef, Australia. The structure was determined to be of formula (I).

L'invention porte sur un nouvel heptapeptide cyclique, la truncamide A, dotée d'une activité antitumorale, isolé à partir d'un Lissoclinum recueilli en Australie sur le Great Barrier Reef. Sa structure a été identifiée comme correspondant à la formule (I).

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