A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61F 6/06 (2006.01) A61F 6/14 (2006.01) A61K 31/56 (2006.01) A61K 47/24 (2006.01) A61K 47/30 (2006.01) A61M 31/00 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01)
Patent
CA 2457979
The invention relates to a delivery system comprising at least one core and a membrane. The core and the membrane consist of an elastomer composition comprising e.g poly (dimethylsiloxane), a siloxane-based elastomer comprising 3,3,3-trifluorpropyl groups attached to the Si-atoms of the siloxane units and/or poly(alkylene oxide) groups, present as alkoxy-terminated grafts or blocks linked to the polysiloxane units by silicon-carbon bonds, or as a mixture of these forms. The delivery system is preferably an implant or an intrauterine, intracervical or intravaginal system.
L'invention concerne un système de libération de médicament comprenant au moins un noyau et une membrane. Le noyau et la membrane sont constitués d'une composition élastomère comprenant p. ex. un poly(diméthylsiloxane), un élastomère à base de siloxane comprenant des groupes 3,3,3-trifluoropropyle reliés aux atomes Si des motifs siloxane et/ou des groupes poly(oxyde d'alcoylène), présents sous forme de greffes ou de blocs à terminaison alcoxy liés aux motifs polysiloxane par des liaisons silicium-carbone, ou sous forme d'un mélange de ces structures. Ce système de libération est de préférence un implant ou un système intra-utérin, intracervical ou intravaginal.
Aaltonen Marko
Ahola Manja
Ala-Sorvari Juha
Haapakumpu Timo
Keinanen Antti
Robic
Schering Oy
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