A diagnostic marker and therapeutic target for cancer

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2626069

The present invention, in general, relates to use of nm23H1-B gene for diagnosing cancer susceptibility and metastatic progression in colon/colorectal cancer. In particular, the present invention relates to identifying the alteration in the expression of nm23H1-B gene on treatment with chemotherapeutic agents for diagnosing cancer susceptibility and metastatic progression in colon/colorectal cancer.

La présente invention concerne, d'une façon générale, l'utilisation du gène nm23H1-B pour diagnostiquer la prédisposition au cancer et la progression métastatique dans le cancer du côlon/colorectal. En particulier, la présente invention concerne l'identification de l'altération de l'expression du gène nm23H1-B lors du traitement avec des agents de chimiothérapie pour diagnostiquer la prédisposition au cancer et la progression métastatique dans le cancer du côlon/colorectal.

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