C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/34 (2006.01) C12Q 1/00 (2006.01) C12Q 1/04 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2366949
There is provided a method for the detection of a disease comprising the following steps: (i) obtaining a biological sample from a human subject; (ii) applying the biological sample to a sialidase substrate which has been immobilised on a solid support medium; and (iii) detecting a change in the immobilised sialidase substrate. The substrate is preferably 5-bromo-4-chloro- 3-indoyl .alpha.-D-N-acetyl neuraminic acid or a salt thereof.
L'invention concerne une méthode de détection d'une maladie consistant à: (I) prélever un échantillon biologique chez un sujet humain, (II) appliquer l'échantillon biologique sur un substrat de sialidase qui a été immobilisé sur un milieu de support solide, et (III) détecter un changement dans le substrat de sialidase immobilisé. Ce substrat est de préférence 5-bromo-4-chloro-3-indoyl .alpha.-D-N-acétyl acide neuraminique, ou un sel dérivé.
Corfield Tony
Millar Michael
Sim & Mcburney
University Of Bristol
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