A direct cellular energy delivery system

Details A direct cellular energy delivery system A direct cellular energy delivery system

A - Human Necessities

61

K

A61K 9/127 (2006.01) A01N 1/00 (2006.01) C12N 1/00 (2006.01) C12N 5/00 (2006.01)

Patent

CA 2641638

A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group consisting of a polar lipid which is not a stable vesicle former, a PEG, a raft former and a fusion protein is provided. The vesicle can further comprise a biomolecule, such as for example ATP. Methods of using the vesicle for delivery of biomolecules are also provided.

L'invention concerne une vésicule lipide comprenant un phospholipide qui consiste en un formateur de vésicule stable et au moins un élément de formation de vésicule instable, ce dernier étant sélectionné dans le groupe constitué d'un lipide polaire qui n'est pas un formateur de vésicule stable, d'un PEG, d'un formateur de radeau et d'une protéine de fusion. La vésicule peut en outre contenir une biomolécule, telle que, par exemple, une ATP. L'invention concerne également des procédés d'utilisation de la vésicule en vue de délivrer des biomolécules.

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