C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/51 (2006.01) A61K 39/29 (2006.01) A61K 39/42 (2006.01) C07H 21/00 (2006.01) C07K 14/005 (2006.01) C07K 14/18 (2006.01) C07K 16/10 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12P 21/08 (2006.01) C12Q 1/70 (2006.01) G01N 33/576 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2107363
2107363 9315111 PCTABS00024 A novel cDNA clone, 20E, has been isolated and characterized as encoding a previously unknown polypeptide antigen recognized by antibodies in the serum of certain patients with non-A, non-B hepatitis (NANBH). The nucleic acid sequence is not represented in the genome of the Hepatitis C Virus (HCV). Neither is the nucleic acid sequence represented in the human genome. The data suggest that the RNA sequence corresponding to clone 20E is contained within the genome of an external infective agent other than HCV, and therefore may represent an additional etiologic agent or contributing factor to the development of NANBH in human patients. The 20E nucleic acid and corresponding polypeptide and respective variants thereof will be useful in a variety of procedures directed at prevention and diagnosis of NANBH.
Arima Terukatsu
Byrne Robert E.
Kieselburg Mark K.
Ryan Terence E.
Saeed Badr
Dade Behring Inc.
Sim & Mcburney
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