A drug-release controlling coating material for long acting...

A - Human Necessities – 61 – K

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A61K 9/32 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2011919

ABSTRACT OF THE DISCLOSURE A coating material for controlling drug release, useful for long acting formulations, e.g., for once-a- day administration, and to a long acting granular composition comprising a drug (especially one conven- tionally difficult to prepare in long acting form) coated with the coating material. This composition may be mixed with other granular drug formulations. The drug-release controlling coating material comprising, in a specific ratio, one specific water- insoluble and low water-permeability polymers and two materials differing from each other in the pH-dependency of their solubility )pH-dependent polymer-materials). - 25 -

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