A dry powder inhaler and system for drug delivery

A - Human Necessities – 61 – M

Patent

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Details

A61M 15/00 (2006.01)

Patent

CA 2728230

A breath-powered, dry powder inhaler (100), a cartridge (150), and a pulmonary- drug delivery system are provided. The dry powder inhaler (100) can be provided with or without a unit dose cartridge (150) for using with the inhaler (100). The inhaler (100) and/or cartridge (150) can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler (100) is compact; can be provided in various shapes and sizes, colors, and comprises a housing (120), a mouthpiece (130), a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable.

La présente invention concerne un inhalateur de poudre sèche commandé par la respiration, une cartouche, et un système dadministration de médicament pulmonaire. Ledit inhalateur de poudre sèche peut être fourni avec ou sans cartouche de dose unitaire à utiliser avec linhalateur. Linhalateur et/ou la cartouche peuvent être fournis avec une formulation dadministration de médicament comprenant, par exemple, une dicétopiperazine et un ingrédient actif, y compris des peptides et des protéines telles que linsuline et le « glucagon-like peptide 1 », destinés au traitement du diabète et/ou de lobésité. Linhalateur de poudre sèche est compact. Il peut être fourni dans des formes, des tailles et des couleurs diverses. Il comprend un boîtier, un embout, une zone de pose de cartouche, et un mécanisme douverture et de fermeture de cartouche de médicament. Ce dispositif est facile à fabriquer, fournit une dose unitaire unique prédosée, est relativement facile à utiliser et peut être réutilisé ou jeté.

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