C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 19/12 (2006.01) C12P 19/14 (2006.01)
Patent
CA 2139506
An enzymatic process is disclosed for the preparation of galactosyl.beta.1,3glycal disaccharides such as Gal.beta.1,3Glucal, an intermediate useful in Lea preparation and an inhibitor of .beta.-galactosidase. The process utilizes .beta.-galactosidase, an enzyme usually used for bond breaking, to form a bond between a galactoside and a glucal such as glycal, a 6-0-C1-C6 acylglucal or 6-0-C1-C6 acetylgalactal.
On divulgue un procédé de préparation de galactosyl-bêta-1,3-glycaldisaccharides à partir du gal-bêta-1,3-glucal, intermédiaire utile dans la préparation de Lea et un inhibiteur de la bêta-galactosidase. Le procédé fait appel à la bêta-galactosidase, une enzyme habituellement utilisée pour briser une liaison, pour former une liaison entre un galactoside et un glucal comme un glycal, un 6-0(acyle en C1-C6)-glucal ou un 6-0(acétyle en C1-C6)-galactal.
Look Gary C.
Wong Chi-Huey
Fetherstonhaugh & Co.
The Scripps Research Institute
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