A foam material for medical use and method for producing same

Details A foam material for medical use and method for producing same A foam material for medical use and method for producing same

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61K 31/722 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01) A61K 47/36 (2006.01) A61L 15/28 (2006.01) A61L 15/42 (2006.01) A61L 26/00 (2006.01)

Patent

CA 2684718

An in situ forming foam for medical applications and a method for making same is described, the method comprising the steps of : preparing a first component, Composition A, comprising an acidic solution of a polycationic polymer selected from the group comprising polymeric amines and polysaccharides; preparing a second component, Composition B, selected from the group comprising a metal carbonate, a metal bicarbonate or a mixture of a metal carbonate and a metal bicarbonate; maintaining said first and second components separately prior to mixing; and mixing said first and second components at an intended site of application. The foam is a mechanically robust but flexible and resilient material wherein the degree and nature of the porosity may be controlled.

La présente invention concerne une mousse se formant in situ pour des applications médicales et un procédé pour la fabriquer, le procédé comprenant les étapes consistant à : préparer un premier composant, de composition A, comprenant une solution acide d'un polymère polycationique choisi dans le groupe comprenant des amines polymères et des polysaccharides ; préparer un second composant, de composition B, choisi dans le groupe comprenant un carbonate métallique, un bicarbonate métallique ou un mélange d'un carbonate métallique et d'un bicarbonate métallique ; maintenir lesdits premier et second composants à part avant le mélange ; et mélanger lesdits premier et second composants à un site d'application prévu. La mousse est un matériau mécaniquement robuste mais flexible et résilient, dans lequel le degré et la nature de la porosité peuvent être contrôlés.

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