A formulation for oral transmucosal administration of...

A - Human Necessities – 61 – K

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Details

A61K 9/00 (2006.01) A61K 9/08 (2006.01) A61K 31/05 (2006.01) A61K 31/167 (2006.01) A61K 31/5377 (2006.01) A61K 31/553 (2006.01) A61K 47/10 (2006.01) A61P 1/06 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2749245

The invention provides a formulation for oral transmucosal administration of at least one active principle with antispasmodic and/or analgesic effect, including said active principle in base form and/or in salt form, an aqueous alcohol solution titrating at least 35° alcohol by weight, said active principle being present in a state of stable and complete dissolution in the aqueous alcohol solution. The invention also provides a method of preparing this formulation and its use for treating spastic crises.

L'objet de l' invention est une formulation pour l'administration par voie trans-muqueuse buccale d'au moins un principe actif à action antispasmodique et/ou antalgique, comprenant ledit principe actif sous forme base et/ou sous forme de sel, une solution hydroalcoolique titrant au moins 35° d'alcool en masse, ledit principe actif étant présent en état de dissolution stable et complète dans la solution hydro-alcoolique. L'invention se rapporte également à un procédé de préparation de cette formulation et à son utilisation pour le traitement le traitement des crises spastiques.

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