A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A23G 3/34 (2006.01) A23L 1/00 (2006.01) A23P 1/02 (2006.01) A61K 9/16 (2006.01) C13K 11/00 (2006.01)
Patent
CA 2058959
The invention relates to a predominantly fructose-based granulated product suitable for use in the manufacture of tablets by direct compression means and consisting of free-flowing granules comprising about 92 % to about 98 % by weight of fructose, about 1 % to about 7 % by weight of a physiologically acceptable polyol selected from sorbitol, maltitol, lactitol, xylitol, mannitol, isomalt and mixtures thereof, optionally with other hydrogenation products or sugars, and less than about 1 % by weight of water. The granulated product is produced according to the invention by agglomerating crystalline fructose ground to a fine particle size by means of an aqueous solution of the polyol, while the fructose is brought to a rapid movement to form a granular product, and drying the granules by means of dry air to a water content of less than 1 %.
L'invention concerne un produit granulé essentiellement à base de fructose, adapté pour être utilisé dans la fabrication de comprimés par compression directe, et composé de granules à écoulement libre comprenant environ 92 % à environ 98 % en poids de fructose, environ 1 % à environ 7 % en poids d'un polyol physiologiquement acceptable choisi entre le sorbitol, le maltitol, le lactitol, le xylitol, le mannitol, l'isomalt ainsi que des mélanges de ceux-ci, facultativement avec d'autres produits d'hydrogénation de sucres, moins d'environ 1 % en poids d'eau. On obtient ledit produit granulé selon l'invention, par agglomération de fructose cristallin moulu jusqu'à obtention d'une granulométrie fine, au moyen d'une solution aqueuse du polyol, tandis que le fructose est amené en mouvement rapide afin de former un produit granulaire et par séchage des granulés au moyen d'air sec jusqu'à une teneur en eau inférieure à 1 %.
Kruger Christof
Makela Matti
Pepper Tammy
Gowling Lafleur Henderson Llp
Xyrofin Oy
LandOfFree
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