C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/57 (2006.01) A61K 38/17 (2006.01) C07K 14/755 (2006.01) C12N 9/64 (2006.01) C12N 11/00 (2006.01) C12N 15/62 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2191053
Fusion proteins of an optionally C-terminally deleted furin derivative, or of a derivative of a furin analogue, and a heterologous sequence, methods of preparing the same and methods of recovering proproteins from proteins by using the proproteins according to the invention are described.
Dans l'invention, on décrit des protéines de fusion d'un dérivé d'un analogue de la furine ou d'un dérivé de la furine ayant facultativement subi une délétion de la portion C-terminale, une séquence hétérologue, des méthodes visant la préparation de ces dérivés et des méthodes permettant de récupérer les proprotéines et de les séparer des protéines en utilisant les proprotéines conformément à l'invention.
Dorner Friedrich
Eibl Johann
Falkner Falko-Guenter
Fischer Bernhard
Schlokat Uwe
Baxter Innovations Gmbh
Fetherstonhaugh & Co.
Immuno Aktiengesellschaft
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