A genetic marker for detection of human papillomavirus

Details A genetic marker for detection of human papillomavirus A genetic marker for detection of human papillomavirus

C - Chemistry, Metallurgy

12

Q

C12Q 1/70 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2741762

The invention provides compositions and methods for the differential detection of high risk forms of HPV from a urine sample provided by a patient. Specifically, the invention provides primers and probes that specifically recognize and bind sequences within the E1 gene of HPV. Detection of high risk forms of HPV identify individuals at risk of developing or in the early stages of cervical carcinoma.

La présente invention concerne des compositions et des procédés de détection différentielle de formes à haut risque de HPV dans un échantillon d'urine d'un patient. L'invention concerne spécifiquement des amorces et des sondes qui reconnaissent spécifiquement des séquences dans le gène E1 du HPV et s'y lient. La détection de formes à haut risque du HPV permet l'identification des individus à risque de développer un ou aux stades précoces du carcinome du col de l'utérus.

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