A glibenclamide-metformin combination for the treatment of...

A - Human Necessities – 61 – K

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A61K 31/64 (2006.01) A61K 31/155 (2006.01)

Patent

CA 2237571

A combination of glibenclamide and metformin such that, when administered in the form of pharmaceutical composition in the treatment of diabetes mellitus of type II, the ratio between the two active principles allows to obtain an optimum therapeutical effect at any time of the progression of the disease, avoiding to make use of the insulin therapy in the most severe cases.

Cette combinaison de glibenclamide et de metformine est telle que, lors de son administration sous la forme d'une composition pharmaceutique dans le traitement du diabète sucré de type II, le rapport entre les deux principes actifs permet d'obtenir un effet thérapeutique optimum à n'importe quel moment de la progression de la maladie, et d'éviter ainsi le recours à la thérapie insulinique dans les cas les plus graves.

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