A human cytomegalovirus combined antigen and its use

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/045 (2006.01) A61K 39/245 (2006.01) C07K 19/00 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2246802

A combined antigen having at least three portions of human cytomegalovirus (HCMV) proteins and characterized by an enhanced ability to bind HCMV-specific antibodies, for use in assays for the detection of HCMV-specific antibodies and as a vaccine to confer protective immunity against HCMV-mediated diseases.

L'invention concerne un antigène combiné présentant au moins trois parties de protéines de cytomégalovirus humain (HCMV). Cet antigène est caractérisé par une meilleure capacité à se lier aux anticorps spécifiques de ce cytomégalovirus, lui permettant d'être utilisé dans des dosages visant à détecter les anticorps spécifiques du cytomégalovirus et comme vaccin pour assurer une immunité de protection contre les maladies induites par le cytomégalovirus.

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