C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 35/12 (2006.01) A61K 38/17 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2261637
This invention provides isolated nucleic acids which encode a wildtype and a mutant human homolog of RAD9. This invention also provides purified and mutant wildtype human homologs of RAD9. This invention also provides methods for determining whether a subject has radiosensitivity; for predicting the effect of radiation therapy or chemotherapy on a subject; for detecting whether a subject has a predisposition to cancer; for treating a subject who is radiosensitive and for preventing or treating cancer in a subject who is radiosensitive. This invention further provides a method of detecting cervical carcinoma in a subject.
L'invention concerne des acides nucléiques isolés codant un homologue humain et de type sauvage de RAD9, un homologue humain et mutant de RAD9, ainsi que des homologues humains, de type sauvage, mutants et purifiés de RAD9. Elle concerne encore des procédés permettant de déterminer si un sujet présente une radiosensibilité, de prédire les effets d'une thérapie ou chimiothérapie de rayonnement sur un sujet, de détecter si un sujet présente une prédisposition au cancer, de traiter un sujet qui est radiosensible et de prévenir ou traiter le cancer chez un tel sujet. L'invention concerne en outre un procédé de détection d'un cancer du col de l'utérus chez une patiente.
Davey Scott K.
Hopkins Kevin M.
Lieberman Howard B.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Queen's University At Kingston
The Trustees Of Columbia University In The City Of New York
LandOfFree
A human radioresistance/cell cycle progression gene does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with A human radioresistance/cell cycle progression gene, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A human radioresistance/cell cycle progression gene will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1803878