A human ribonucleotide reductase m2 subunit

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 21/02 (2006.01) A01N 43/04 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) A61K 49/00 (2006.01) C07H 21/04 (2006.01) C12N 9/02 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2513149

An isolated nucleic acid containing a human ribonucleotide reductase M2 subunit promoter sequence or genomic sequence. Also disclosed are methods of determining whether a subject is suffering from or at risk for developing a cell proliferation-associated disorder, identifying a compound for treating a cell proliferation-associated disorder, treating a cell proliferation- associated disorder, and developing a procedure for treating a cell proliferation-associated disorder.

L'invention concerne un acide nucléique isolé contenant une séquence promoteur ou une séquence génomique d'une sous-unité de ribonucléotide réductase M2 humaine. L'invention concerne également des procédés permettant de déterminer si un sujet souffre d'un trouble associé à une prolifération cellulaire ou risque d'en développer un, des procédés permettant d'identifier un composé destiné au traitement d'un trouble associé à une prolifération cellulaire, des procédés permettant de traiter un trouble associé à une prolifération cellulaire, ainsi que des procédés permettant de développer une procédure destinée au traitement d'un trouble associé à une prolifération cellulaire.

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