A knockout mouse for the tumor suppressor gene anx7

Details A knockout mouse for the tumor suppressor gene anx7 A knockout mouse for the tumor suppressor gene anx7

G - Physics

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N

G01N 33/50 (2006.01) C07K 14/47 (2006.01) C12N 15/85 (2006.01) G01N 33/574 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2378292

A knockout transgenic mouse containing a nonfunctional allele of the tumor suppressing gene, annexin VII. This mouse is used as a screening model for potential therapeutic agents useful in the treatment of tumors resulting from an annexin tumor suppressor disease.

L'invention concerne une souris transgénique knockout contenant un allèle non fonctionnel du gène suppresseur de tumeur, l'annexine VII. Cette souris est utilisée comme modèle de criblage d'agents thérapeutiques potentiels utiles dans le traitement de tumeurs ayant pour origine une maladie liée au gène d'annexine suppresseur de tumeur.

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