A ligand for enhancing oral and cns delivery of biological...

Details A ligand for enhancing oral and cns delivery of biological... A ligand for enhancing oral and cns delivery of biological...

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 47/48 (2006.01) C07K 7/06 (2006.01) C07K 14/505 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2408387

Provided herein is a novel and useful Ligand comprising a peptide comprising an amino acid sequence of SEQ. ID. NO.:6, an analog, a derivative, or a variant thereof, which increases the absorption of biological agents across the blood brain barrier and the gastrointestinal barrier. As a result, a Ligand of the present invention increases the bioavailability of biological agents administered orally.

Cette invention se rapporte à un nouveau ligand utile comprenant un peptide contenant une séquence d'acide aminé de numéro d'identification de séquence 6, un analogue, un dérivé ou un variant de celui-ci, qui augmentent l'absorption d'agents biologiques à travers la barrière hémato-encéphalique et la barrière gastro-intestinale. Ainsi, ce ligand améliore la biodisponibilité d'agents biologiques administrés par voie orale.

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