A lysosomal-associated multispanning membrane protein,...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2263098

This invention relates to the discovery of a nucleic acid molecule which encodes a hematopoietic-specific protein, termed LAPTM5. The expression pattern of the gene together with evidence that the protein interacts with ubiquitin indicates that the protein has a functional role during embryogenesis and in adult hematopoietic cells.

Cette invention concerne une molécule d'acide nucléique codant une protéine à spécificité hématopoïétique et dénommée LAPTM5. Le diagramme d'expression du gène ainsi que la preuve d'interaction entre la protéine et l'ubiquitine, indiquent que ladite protéine joue un rôle fonctionnel lors de l'embryogenèse ainsi que dans les cellules hématopoïétiques adultes.

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