A medical product comprising tiotropium in a moisture-proof...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/14 (2006.01) A61J 1/00 (2006.01) A61K 31/46 (2006.01) A61M 15/00 (2006.01) A61P 11/06 (2006.01) A61P 11/08 (2006.01)

Patent

CA 2547781

The invention discloses a medical product for use in a treatment of respiratory disorders, and comprises a metered dose of a tiotropium dry powder formulation, directly loaded and sealed into a container made to act as a dry high barrier seal to prevent the capture and ingress of moisture into the tiotropium powder. The dose of tiotropium is further adapted for inhalation and the container is so tight that the efficacy of the dose when delivered is unaffected by moisture. In a further aspect of the invention a type of inhaler is illustrated, which may accept at least one sealed, moisture~tight container of a dose of tiotropium, to deliver the dose with a consistent fine particle dose, over the expected shelf life of the product.

L'invention se rapporte à un produit médical qui s'utilise dans le traitement des troubles respiratoires, et contient une dose mesurée d'une formulation de poudre sèche de tiotropium, directement chargée et scellée dans un contenant conçu pour servir de barrière très étanche et sèche afin d'empêcher la saisie et l'entrée d'humidité dans la poudre de tiotropium. La dose de tiotropum est ensuite adaptée en vue d'une inhalation et l'étanchéité du contenant est telle que l'efficacité de la dose est insensible à l'humidité. Dans un autre aspect, l'invention porte sur un type d'inhalateur, qui peut recevoir au moins un contenant étanche à l'humidité et scellé d'une dose de tiotropium, afin d'administrer la dose avec une dose à particules fines consistante, pendant la durée de conservation prévue du produit.

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