A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 31/4188 (2006.01) A61K 39/395 (2006.01) A61K 51/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2522580
The present invention describes the use of an agent endowed with tumour tropism in combination with another agent with anticancer activity and with an affinity for the first agent for the preparation of a medicament useful for the two-step perioperative therapy of solid tumours. The advantages of the present invention consist in the greater, effective localisation of its anticancer activity, in the reduction of the number of administration steps and in the possibility of reducing the anticancer doses, with a resulting decrease in side effects, but without any loss of efficacy.
La présente invention a trait à l'utilisation d'un agent à tropisme tumoral en combinaison avec un autre agent à activité anticancéreuse et ayant une affinité pour le premier agent pour la préparation d'un médicament utile pour la thérapie peropératoire en deux étapes de tumeurs solides. La présente invention présente les avantages d'une localisation efficace et supérieure de son activité anticancéreuse, la réduction du nombre d'étapes d'administration et la possibilité de réduire les doses anticancéreuses, entraînant une diminution des effets secondaires, mais sans aucune perte d'efficacité.
Carminati Paolo
Paganelli Giovanni
Veronesi Umberto
Fetherstonhaugh & Co.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a.
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