A membrane-bound netrin

Details A membrane-bound netrin A membrane-bound netrin

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) C12P 19/34 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61P 25/00 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2324167

It is an object of the present invention to identify unknown members of the UNC-6/Netrin family that are predicted to exist and analyze their function in organisms, for the purposes of elucidating the function of Netrin molecules in the brain of vertebrate animals, providing suitable treatment for brain damage caused by disease, and allowing the promotion of normal neural pathway formation during transplant treatment and the like. Specifically, the present invention provides a membrane- bound Netrin having a hydrophobic region at its C-terminus, wherein the hydrophobic region is able to bind to the cell membrane by means of glycosylphosphatidylinositol (GPI)

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