A method and compositions for treatment of insulin-dependant...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 38/28 (2006.01) A61K 38/46 (2006.01) A61K 38/51 (2006.01) C07K 14/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2267063

The present invention relates generally to a method of prophylaxis and treatment of autoimmune disease conditions and agents useful for same. More particularly, the present invention contemplates mucosa-mediated tolerance to protect against or ameliorate the symptoms associated with autoimmune pathology. Even more particularly, the present invention provides a method for preventing clinical diabetes or preventing or reducing or ameliorating the effects of clinical diabetes by the aerosol administration of diabetes- associated autoantigens to mucosal surfaces.

La présente invention concerne, en général, un procédé de prophylaxie et de traitement des états pathologiques de nature auto-immunitaire et des agents convenant auxdit états. La présente invention concerne, plus particulièrement, une tolérance induite par les muqueuses visant à protéger contre ladite pathologie ou à réduire les symptômes associés à une pathologie auto-immune. Ladite invention concerne, plus particulièrement encore, un procédé de prévention du diabète clinique ou de prévention, de réduction ou d'amélioration des effets du diabète clinique sur les surfaces des muqueuses par administration par aérosol d'auto-antigènes liés au diabète.

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