A method and device for analysis of charged molecules by...

G - Physics – 01 – N

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G01N 27/447 (2006.01) B01D 57/02 (2006.01) B01D 61/00 (2006.01) B01D 71/56 (2006.01) C07K 1/28 (2006.01)

Patent

CA 2405501

The invention provides a novel solution isofocusing device and method that can reproducibly fractionate charged molecules into well-defined pools. This approach can be applied to complex charged molecule samples, such as eukaryotic proteome samples where reproducible resolution and quantitation of greater than 10,000 protein components is feasible.

L'invention concerne un dispositif et un procédé de focalisation isoélectrique d'une solution qui permettent de fractionner de façon reproductible des molécules chargées en groupes bien définis. Cette approche peut s'appliquer à des échantillons moléculaires chargés complexes, tels que des échantillons protéomiques eucaryotes où une résolution reproductible et une quantification supérieure à 10.000 composants protéiques peuvent être réalisées.

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