A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 15/00 (2006.01) A61M 11/00 (2006.01) A61M 15/08 (2006.01) B05B 1/02 (2006.01) B05B 11/02 (2006.01) G01N 11/00 (2006.01)
Patent
CA 2298596
The present invention relates to a method for administering a pharmaceutical preparation comprising at least one active substance to the olfactory region of a human. The method comprises administering a unit dose of the preparation by ejection from a nasal spray device (1) through a nostril of a human, the device and the pharmaceutical preparation being adapted so that the spray angle (3) is at the most 35~. The method is useful for the treatment of diseases affecting the olfactory organ, the brain and the central nervous system. The present invention also relates to a nasal spray device (1) comprising a pharmaceutical preparation. The pharmaceutical preparation preferably contains a viscosity enhancing agent and the pharmaceutical preparation preferably has a dynamic viscosity in the range of 5-300 cP.
Cette invention se rapporte à un procédé servant à administrer dans l'organisme d'un sujet au niveau de l'aire olfactive une préparation pharmaceutique contenant au moins une substance active. Ce procédé consiste à administrer une dose unitaire de cette préparation en l'injectant d'un spray nasal (1) dans une narine, le spray et la préparation pharmaceutique étant conçus pour que l'angle d'injection (3) ne dépasse pas 35·. Ce procédé sert à traiter les maladies affectant l'organe olfactif, le cerveau et le système nervo-central. Cette invention se rapporte également à un spray nasal (1) comprenant une telle préparation pharmaceutique. Cette préparation pharmaceutique renferme de préférence un agent améliorant la viscosité et elle présente de préférence une viscosité dynamique comprise entre 5 et 300 cP.
Blake Cassels & Graydon Llp
Gizurarson Sveinbjorn
Lyfjathroun Biopharmaceuticals Hf.
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