A method for analyzing psa, and a method for distinguishing...

G - Physics – 01 – N

Patent

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G01N 33/574 (2006.01)

Patent

CA 2751400

A method for distinguishing prostate cancer from prostatic hypertrophy using the method for analyzing PSA and an analysis kit of PSA are provided. An object of the present invention can be solved by being brought into contact a lectin having an affinity for .beta.-N-acetylgalactosamine residues and/or a lectin having an affinity for fucose .alpha.(1, 2) galactose residues with a sample possibly containing PSA, to determine an amount of PSA having an affinity for the lectin. A method for distinguishing prostate cancer from prostatic hypertrophy can be provided by this method.

L'invention concerne un procédé d'analyse de l'APS permettant de différencier un cancer de la prostate d'une prostatomégalie avec fiabilité. Elle concerne également un nécessaire d'analyse de l'APS. Le procédé d'analyse de l'APS comprend le fait de mettre une lectine ayant une affinité pour un résidu ß-N-acétylgalactosamine et/ou une lectine ayant une affinité pour un résidu fucose a(1,2)galactose en contact avec un échantillon dont on soupçonne qu'il contient de l'APS, et de déterminer la quantité d'APS ayant une affinité pour la lectine. Le procédé peut fournir un moyen de différencier un cancer de la prostate d'une prostatomégalie.

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