C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/14 (2006.01) C07K 14/37 (2006.01) C12N 1/15 (2006.01) C12N 15/80 (2006.01)
Patent
CA 2382468
This invention relates to a method for decreasing the foam formation during cultivation of a microorganism and to a method for producing an enhanced amount of a product of interest. The method comprises that the microorganism is modified in such a way that the microorganism does not produce an essential amount of at least one of the proteins, polypeptides or peptides associated with foam formation during cultivation of the unmodified microorganism. In particular the method comprises that the microorganism is modified not to produce an essential amount of amphipathic or hydrophobic proteins, polypeptides or peptides.
L'invention concerne une méthode visant à réduire la formation de mousse pendant la culture d'un microorganisme, et une méthode permettant de produire une plus grande quantité d'un produit d'intérêt. Selon cette méthode, le microorganisme est modifié de façon à ne pas produire en quantité importante au moins une des protéines, un des polypeptides ou un des peptides associés à la formation de mousse pendant la culture du microorganisme non modifié. La méthode consiste en particulier à modifier le microorganisme afin que celui-ci ne produise pas en quantité importante des protéines, des polypeptides ou des peptides amphipathiques ou hydrophobes.
Bailey Michael
Nakari-Setala Tiina
Penttila Merja
Tenkanen Maija
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Valtion Teknillinen Tutkimuskeskus
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