A method for designing and screening random libraries of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07H 21/00 (2006.01) C12N 15/10 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12P 19/34 (2006.01) G01N 33/53 (2006.01) G01N 33/532 (2006.01)

Patent

CA 2408652

Provided herein are methods for producing novel and useful multidimensional libraries (MDL) comprising molecules of varying lengths, wherein the molecules comprise a functional unit that potentially interacts with a target molecule, and a structural unit. Also provided are novel oligonucleotides, vectors, transformed and transfected unicellular hosts, as well as kits for screening molecules of a multidimensional library for their potential interaction with a target molecule.

L'invention porte sur des procédés de production de nouvelles bibliothèques multidimensionnelles, utiles, comprenant des molécules de différentes longueurs. Ces molécules comprennent une unité fonctionnelle ayant une interaction potentielle avec une molécule cible et une unité structurale. L'invention porte également sur de nouveaux oligonucléotides, vecteurs, hôtes unicellulaires transformés et transfectés, ainsi que sur des kits de recherche systématique de molécules d'une bibliothèque multidimensionnelle pour leur interaction potentielle avec une molécule cible.

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