C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/47 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2332657
The present invention relates to a method for detecting an aberrant animal- derived prion gene wherein the method comprises steps of introducing a prion gene of an animal into a mouse to produce a prion gene modified mouse and determining that the prion gene is aberrant when the prion gene modified mouse exhibits heart anomalies; a prion gene modified mouse which exhibits heart anomalies; and a method for detecting drugs which reduce abnormal waves in an electrocardiogram of the mouse.
Itohara Shigeyoshi
Onodera Takashi
Tsubone Hirokazu
Riken
Smart & Biggar
LandOfFree
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