A method for detecting defects in protein c/protein s...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/56 (2006.01) C12Q 1/37 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2155503

The present invention relates to a screening method which generally indicates a disturbance of the protein C/protein S system of blood clotting. The endogenous protein C in a sample is activated by adding a protein C activator and the clotting time is measured. A disturbance of the protein C/protein S system is detected by a less pronounced prolongation of the clotting time compared to prolongation of the clotting time in a normal plasma.

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