A method for determination of sirolimus stability and...

G - Physics – 01 – N

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G01N 21/35 (2006.01) B01D 9/02 (2006.01) C07D 498/18 (2006.01) G01J 3/28 (2006.01)

Patent

CA 2749807

The present disclosure provides solution to the problems involved in determining the crystallinity of sirolimus. More particularly, the instant disclosure is successful in providing a method to determine crystallinity of sirolimus or its analogues using Near-Infrared [NIR] spectroscopy. Also, the instant disclosure provides a method for crystallization of sirolimus or its analogues.

La présente invention propose une solution aux problèmes rencontrés dans la détermination de la cristallinité du sirolimus. La présente invention concerne plus particulièrement un procédé de détermination de la cristallinité du sirolimus ou de ses analogues à l'aide d'une spectroscopie proche infrarouge [NIR]. La présente invention concerne en outre un procédé de cristallisation du sirolimus ou de ses analogues.

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