A method for diagnosis and prognosis of multiple sclerosis

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) G01N 1/00 (2006.01) G01N 33/542 (2006.01) G01N 33/564 (2006.01)

Patent

CA 2501873

This invention provides methods utilizing detection/quantification of autoantibodies to specific epitopes of myelin components (e.g. to conformational epitope of myelin/oligodendrocyte glycoprotein (MOG)) for the definite diagnosis, and/or staging or typing, and/or prognosis of multiple sclerosis.

L'invention concerne des méthodes utilisant la détection/quantification d'autoanticorps contre des épitopes spécifiques de composants de la myéline (par exemple, contre un épitope conformationnel de myéline/oligodendrocyte glycoprotéine (MOG) afin d'établir un diagnostic précis, et/ou de déterminer le stade ou le type, et/ou de faire un pronostic de la sclérose en plaques.

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