A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/655 (2006.01) A61K 9/16 (2006.01) A61K 9/26 (2006.01) A61K 9/52 (2006.01) A61K 31/43 (2006.01) A61K 31/60 (2006.01) B01J 2/10 (2006.01)
Patent
CA 2094030
A melt granulating method for the production of pellets (spheres) which contain a therapeutically active substance of high- dosage type. The method is characterized by: (i) mechanically working a mixture which contains (a) the active substance in cohe- sive form and (b) a binder (melting point 40°C - 100°C) while supplying sufficient energy for the binder to melt and to form spherical overwetted pellets; (ii) adding further cohesive substance, while maintaining the mechanical working; (iii) interrupting the mechanical working and supply of energy and cohesive substance when the desired mean particle size of dry pellets (spheres) has been achieved; and (iv) removing the smallest and largest particles and dividing the remaining pellets into dosage batches. A novel pharmaceutical composition containing a dosage of 300 - 500 mg of pellets obtainable from the process.
Holm Per
Kristensen Arne
Kabi Pharmacia Ab
Pharmacia Aktiebolag
Ridout & Maybee Llp
LandOfFree
A method for drug formulation and a pharmaceutical composition does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with A method for drug formulation and a pharmaceutical composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A method for drug formulation and a pharmaceutical composition will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1408500