A method for enhancing the lowering of plasma cholesterol...

A - Human Necessities – 61 – K

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A61K 31/366 (2006.01) A61K 9/00 (2006.01) A61K 31/00 (2006.01) A61K 31/215 (2006.01) A61K 31/365 (2006.01) A61K 47/00 (2006.01)

Patent

CA 2003385

51/MW29 IX141-CANADA TITLE OF THE INVENTION A SYSTEM FOR ENHANCING THE LOWERING OF PLASMA CHOLESTEROL LEVELS ABSTRACT OF THE DISCLOSURE A system for enhancing the lowering of plasma cholesterol levels in a subject in need thereof which comprises a time-controlled system for the administration of a nontoxic therapeutically effective amount of an HMG-CoA reductase inhibitor to said subject which affords an equivalent or improved reduction of plasma cholesterol levels while significantly reducing the amount of HMG-CoA reductase inhibitor circulating in the bloodstream of the subject when compared to the oral administration of a conventional rapid release dosage form.

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