A method for improving the half-life of soluble...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61F 6/06 (2006.01) A61F 13/00 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 38/17 (2006.01) A61K 39/40 (2006.01) C07K 16/12 (2006.01)

Patent

CA 2369762

This invention relates to methods of increasing the half-life of a viral- specific ligand on a mucosal membrane by modifying the viral-specific ligand to bind the bacteria colonized on the mucosal membrane. The invention also provides a chimeric molecule comprising a viral-specific ligand and a bacterial-specific ligand.

L'invention concerne des procédés destinés à augmenter la demi-vie d'un ligand spécifiquement viral sur une membrane de muqueuse en modifiant le ligand spécifiquement viral de manière à lier les bactéries colonisant la membrane de muqueuse. L'invention concerne également une molécule chimérique comprenant un ligand spécifiquement viral et un ligand spécifiquement bactérien.

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