C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 16/00 (2006.01) C07K 16/30 (2006.01) C07K 16/46 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2262405
The present invention provides a method for inhibiting immunoglobulin-induced toxicity resulting from immunotherapy in a subject comprising administering an immunoglobulin or Ig fusion protein molecule to the subject, the immunoglobulin molecule having a variable region and a constant region, the immunoglobulin molecule being modified prior to administration by inactivation of at least a portion of the constant region.
L'invention concerne un procédé servant à inhiber la toxicité provoquée par les immunoglobulines provenant de l'immunothérapie chez un individu, ce qui consiste à administrer à cet individu une molécule d'immunoglobuline ou de protéine de fusion d'immunoglobuline Ig, la molécule d'immunoglobuline possédant une zone variable et une zone constante, ladite molécule d'immunoglobuline étant modifiée préalablement à son administration par inactivation d'au moins une partie de la zone constante.
Rosok Mae Joanne
Yelton Dale E.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
LandOfFree
A method for inhibiting immunoglobulin-induced toxicity... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with A method for inhibiting immunoglobulin-induced toxicity..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A method for inhibiting immunoglobulin-induced toxicity... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1404219