A method for placing a photo-cross-linking agent at specific...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2333330

This invention describes novel photoactive ribonucleotides that contain photo- cross-linking agents placed at specific internal positions within a ribonucleotide. The invention also provides methods for identifying novel, sequence-specific target molucules, using the photoactive ribonucleotides of the invention, as well as improved nucleic acid hybridization analysis methods.

L'invention concerne de nouveaux ribonucléotides photosensibles qui contiennent des agents de photoréticulation placés à des positions internes spécifiques dans un ribonucléotide. L'invention concerne également des procédés permettant d'identifier de nouvelles molécules cibles spécifiques de séquence au moyen des ribonucléotides photosensibles de l'invention, ainsi que des procédés améliorés d'analyse d'hybridation d'acides nucléiques.

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