A method for preparing macrocycles

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 1/00 (2006.01) C07C 6/06 (2006.01) C07K 5/12 (2006.01)

Patent

CA 2722867

The present invention is directed to a method for the preparation of macrocyclic compounds of formula (I), com-prising the step of cyclizing a diene of formula (II), in the presence of a catalyst, wherein R1-R6, A, W and V are as defined herein. The present invention is also directed to intermediate compounds of formula (II).

La présente invention porte sur un procédé pour la fabrication de composés macrocycliques représentés par la formule (I), comprenant l'étape de cyclisation d'un diène représenté par la formule (II), en présence d'un catalyseur, où R1-R6, A, W et V sont tels que définis dans la description. La présente invention porte également sur des composés intermédiaires représentés par la formule (II).

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