H - Electricity – 01 – J
Patent
H - Electricity
01
J
358/9
H01J 49/04 (2006.01) G01N 1/42 (2006.01) G01N 30/84 (2006.01) G01N 30/02 (2006.01) G01N 30/72 (2006.01)
Patent
CA 2025771
2025771 9008398 PCTABS00001 A method is disclosed for the processing and preparation of a sample (7) of one or more nonvolatile or thermally labile molecules for mass spectral analysis which comprises providing a solution of such molecules dissolved in a solvent, freezing the solution of dissolved molecules to form a frozen solution (8), and exposing the frozen solution to a source of energy (30), to desorb the molecules to be analyzed from the surface of the frozen solution. The desorbed molecules may be directly ionized during desorption or may be photoionized after desorption (40), if necessary, and then conventionally analyzed in a mass spectrometer (60). The method mitigates or minimizes possible fragmentation or clustering of such large molecules during desorption from the frozen sample as well as providing a more reliable and uniform desorption. If desired the desorbed molecules may be subjected to a separate and controlled fragmentation step prior to entering the final mass spectral analysis zone. The method may be interfaced with liquid chromatography equipment.
Gowling Lafleur Henderson Llp
Sri International
LandOfFree
A method for preparing samples for mass analysis by... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with A method for preparing samples for mass analysis by..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A method for preparing samples for mass analysis by... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1623810