A method for producing bicyclic .gamma.-amino acid derivative

C - Chemistry – Metallurgy – 07 – C

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C07C 227/34 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61P 25/04 (2006.01) A61P 43/00 (2006.01) C07C 229/32 (2006.01) C07B 57/00 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2756750

The problem to be solved is to provide a method for producing a compound having excellent activity as an .alpha.2.delta. ligand. The solution thereto is a method for producing a compound represented by the general formula (I) or a salt thereof by optical resolution: (see formula I) [in the formula, R1: a hydrogen atom or a C1-C6 alkyl group, and R2: a hydrogen atom or a protective group for the carboxy group]

La présente invention a pour objet une méthode de production d'un composé qui possède une activité excellente en tant que ligand a2d. L'invention a pour objet spécifique une méthode de production d'un composé représenté par la formule (I) ou de l'un de ses sels à l'aide d'une résolution optique. Dans la formule (I), R1 représente un atome d'hydrogène ou un groupe alkyle en C1 à C6 ; et R2 représente un atome d'hydrogène ou un groupe carboxy-protecteur.

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