A method for producing l-amino acid

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/00 (2006.01) C12N 15/31 (2006.01) C12P 13/04 (2006.01) C12P 13/06 (2006.01) C12P 13/08 (2006.01) C12P 13/12 (2006.01)

Patent

CA 2744852

A bacterium which belongs to the family Enterobacteriaceae, and has an ability to produce L-lysine, L-threonine, L-asparagine, L-aspartic acid, L-methionine, L-alanine, L-isoleucine or L-homoserine, and has been modified so that expression of gltP gene and/or gltS gene thereof is increased is cultured in a medium to produce and accumulate the L-amino acid in the medium or cells.

Selon la présente invention, la L-lysine, la L-thréonine, la L-asparagine, lacide L-aspartique, la L-méthionine, la L-alanine, la L-isoleucine ou la L-homosérine peuvent être produits par culture dune bactérie dans un milieu de culture pour produire et accumuler lacide aminé L dans le milieu de culture ou une cellule de la bactérie, où la bactérie est capable de produire lacide aminé L, appartient à la famille Enterobacteriaceae, et est modifiée de sorte que lexpression du gène gltP et/ou du gène gltS soit augmentée.

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